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From the published research

The lactam-bridged molecule, called Melanotan-II (MT-II), has the structure Ac-Nle4-Asp5-His6-D-Phe7-Arg8-Trp9-Lys10 alpha-MSH4-10-NH2 (MT-II) and has superpotent melanotropic activity in vitro.

— Dorr et al., Life Sciences (1996) doi:10.1016/0024-3205(96)00160-9

Melanotan II — Frequently Asked Questions

What is Melanotan II researched for?

In research models, Melanotan II has been observed to activate melanocortin receptors (MC1R-MC5R). MC1R activation in melanocytes stimulates melanin production, MC4R activation affects arousal and appetite pathways, and MC3R activation influences energy metabolism in research models. Areas of research interest include: Natural melanin production promotion studied in research; UV-protective skin darkening effects investigated; Reduced UV exposure for melanogenesis studied.

Is Melanotan II third-party tested?

Yes. Each batch of Melanotan II is analyzed by an independent third-party laboratory. Batch MEL01 (results dated January 9, 2026) reported average purity of 99.47% and average mass of 10.21 mg. Full Certificate of Analysis documentation is available for this product.

What does published research say about Melanotan II?

Originally developed at the University of Arizona for melanin production research. Published studies demonstrate effective melanogenesis and photoprotection effects, though regulatory status varies by region. This page cites 3 published references for further reading.

Who typically studies Melanotan II in a laboratory setting?

Researchers studying melanocortin receptor pharmacology, laboratories investigating melanogenesis pathways, and institutions exploring UV-protective peptide biology.

How should Melanotan II be reconstituted and stored?

This peptide is supplied as a lyophilized (freeze-dried) powder. Bacteriostatic water is required to reconstitute it before use and is not included with this product. Store lyophilized (powder) form at room temperature or refrigerated. After reconstitution, store refrigerated (2-8°C) and use within 30 days. Protect from light.

Where can I buy Melanotan II in Canada?

MyPeptide is a Canadian supplier of research peptides based in Mississauga, Ontario. Melanotan II is stocked domestically and ships to research customers nationwide — including Toronto, Vancouver, Calgary, Edmonton, Ottawa, and Montreal. Every order includes third-party Certificate of Analysis documentation for the batch shipped.

Does MyPeptide ship Melanotan II across Canada?

Yes. Melanotan II ships from within Canada to every province and territory, with fast domestic delivery and no international customs delays. Orders are dispatched with tracking, and all products are sold strictly for laboratory and research use only.

Research peptide reference page

Melanotan II

A synthetic analog of alpha-melanocyte-stimulating hormone studied in research for promoting melanin production through melanocortin receptor activation. Also investigated for effects on appetite and libido through MC3R/MC4R pathways.

CAS number: 121062-08-6.

In research models, Melanotan II has been observed to activate melanocortin receptors (MC1R-MC5R). MC1R activation in melanocytes stimulates melanin production, MC4R activation affects arousal and appetite pathways, and MC3R activation influences energy metabolism in research models.

Researchers studying melanocortin receptor pharmacology, laboratories investigating melanogenesis pathways, and institutions exploring UV-protective peptide biology.

Melanotan II is supplied for laboratory research use only. It is not for human or animal use, clinical use, diagnostic use, therapeutic use, or personal-use protocols.

Each MyPeptide reference page is organized around product identity, documentation, and research context rather than medical claims, dosing instructions, or personal-use outcomes.

Use the related links on this page to move between the catalog, COA records, policy pages, and supporting research guides while staying within the research-use-only scope.

Batch documentation, product identity, and compliance context are kept close together so qualified purchasers can review the material before continuing through the storefront.

Research context

Originally developed at the University of Arizona for melanin production research. Published studies demonstrate effective melanogenesis and photoprotection effects, though regulatory status varies by region.

Store lyophilized (powder) form at room temperature or refrigerated. After reconstitution, store refrigerated (2-8°C) and use within 30 days. Protect from light.